An Ultralong Bovine CDRH3 that Targets a Conserved, Cryptic Epitope on SARS-CoV and SARS-CoV-2
Matthew J. Burke, James N.F. Scott, Thomas C. Minshull, Peter G. Stockley, Antonio N. Calabrese, Joan Boyes
The paper isolates a bovine ultralong CDRH3 antibody that targets a conserved, cryptic epitope on SARS-CoV and SARS-CoV-2, demonstrating its neutralizing activity through specific epitope recognition.
bioRxiv · Apr 6, 2022 · PreprintMolecular Biology