Systemic delivery of drug-free polymeric nanoparticles reprograms innate immunity in a sex-dependent manner after spinal cord injury
Jaechang Kim, Irina V. Kalashnikova, Ruby Maharjan, Fernanda Stapenhorst França, Daniel Kolpek, James Ogidi, John C. Gensel, Jonghyuck Park
This study shows that drug-free polymeric nanoparticles improve locomotor recovery after spinal cord injury in both sexes through sex-specific immune mechanisms.
bioRxiv · Mar 9, 2026 · PreprintBioengineering