John C. Gensel

This study shows that High-Low training improves respiratory function and reduces anxiety-like behaviors in a rodent model of chronic spinal cord injury.

This study shows that drug-free polymeric nanoparticles improve locomotor recovery after spinal cord injury in both sexes through sex-specific immune mechanisms.

This study shows that sustained inflammation in chronic spinal cord injury, mediated by macrophages and microglia, inhibits axon regeneration, and that reducing inflammation can increase axon density in specific populations.

This study shows that PTEN knockout via retrogradely transported AAVs can restore locomotor function in both acute and chronic spinal cord injury, but functional improvements are not sustained long-term.

The paper identifies soluble TNF receptor 1 (sTNFR1) as a therapeutic target for spinal cord injury using multi-dimensional analysis of preclinical data.