Curcumin Analogues Trigger HMOX1-Mediated Ferroptosis to Halt Endometrial Cancer Growth
Xiangxiang Wu, Jamie L. Padilla, Lane E. Smith, Lavanya Goodla, Kimberly Kay Leslie, Xiang Xue
This study shows curcumin analogues HO-3867 and AKT-100 induce HMOX1-mediated ferroptosis and apoptosis, effectively inhibiting endometrial cancer cell growth.
bioRxiv · Nov 18, 2025 · PreprintCancer Biology