Author

Kimberly Kay Leslie

University of New MexicoORCID 0000-0002-2704-8990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jamie L. Padilla· 2 shared Lane E. Smith· 2 shared Xiangxiang WuiD· 2 shared Alexander Goss· 1 shared Christine M. PaukeniD· 1 shared Cynthia M. TshibanguiD· 1 shared Daisy Belmares-Ortega· 1 shared Geneva L. WilliamsiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Jamie L. Padilla

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 31, 2026

Auranofin potentiates cisplatin response through context-dependent NOTCH-associated signaling states in endometrial cancer

Robert J. Lake, Cynthia M. Tshibangu, Niko J Candia…·Hua-Ying Fan

This study shows auranofin enhances cisplatin response in endometrial cancer by modulating NOTCH signaling, with context-dependent effects on tumor models.

DOI 10.64898/2026.05.27.728338

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 18, 2025

Curcumin Analogues Trigger HMOX1-Mediated Ferroptosis to Halt Endometrial Cancer Growth

Xiangxiang Wu, Jamie L. Padilla, Lane E. Smith…·Xiang Xue

This study shows curcumin analogues HO-3867 and AKT-100 induce HMOX1-mediated ferroptosis and apoptosis, effectively inhibiting endometrial cancer cell growth.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 6, 2025

The novel curcumin analogue AKT-100 targets both mutant p53 and STAT3 in gynecologic cancer cells

Geneva L. Williams, Lane E. Smith, Jamie L. Padilla…·Kimberly Kay Leslie

This paper develops AKT-100, a curcumin analogue that targets mutant p53 and STAT3 in gynecologic cancer cells, showing cytotoxicity and synergy with existing therapies.

1 citation

humanproteomics

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