Inactivated voltage-gated sodium channels are preferentially targeted in cinacalcet block of mouse neocortical action potentials
Jamie S. Lindner, Salil R. Rajayer, Briana J. Martiszus, Stephen M. Smith
This study investigates how cinacalcet inhibits voltage-gated sodium channels in mouse neocortical neurons, showing it preferentially targets fast-inactivated states and alters neuronal excitability non-linearly.
Frontiers in Physiology · Dec 19, 2022Peer-reviewedNeuroscience