Melanopsin-dependent direct photic effects are equal to clock-driven effects in shaping the nychthemeral sleep-wake cycle
Jeffrey T. Hubbard, Mio Kobayashi Frisk, Élisabeth Ruppert, Jessica W. Tsai, Fanny Fuchs, Ludivine Robin-Choteau, Jana Husse, Laurent Yves Calvel, Gregor Eichele C, Paul Franken, Patrice Bourgin
The paper shows that direct photic effects and circadian-driven effects equally shape the sleep-wake cycle in mice, with melanopsin mediating most direct light effects.
bioRxiv · Feb 21, 2020 · PreprintNeuroscience