Author

Jeffrey T. Hubbard

University of LausanneORCID 0000-0002-0405-9398Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:electronic health records· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Paul FrankeniD· 5 shared Yann Emmenegger· 4 shared Charlotte N. HoriD· 2 shared Marieke MB HoekstraiD· 2 shared Valérie MongrainiD· 2 shared Antoine AdamantidisiD· 1 shared Christos Polysopoulos· 1 shared Élisabeth RuppertiD· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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5 shared papersNeuroscience

Paul FrankenORCID

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Author profile →

5 papers

Recent·Most cited

Cortical miR-709 links glutamatergic signaling to NREM sleep EEG slow waves in an activity-dependent manner

Konstantinos Kompotis, Géraldine M. Mang, Jeffrey T. Hubbard, Sonia Jimenez, Yann Emmenegger, Christos Polysopoulos, Charlotte N. Hor, Leonore Wigger, Sébastien S. Hébert, Valérie Mongrain, Paul Franken

This study shows that miR-709 regulates NREM sleep EEG slow waves by linking glutamatergic signaling to neuronal activity through endosomal trafficking.

Proceedings of the National Academy of Sciences · Jan 11, 2024Peer-reviewedNeuroscience

Reassessing the validity of slow-wave dynamics as a proxy for NREM sleep homeostasis

Jeffrey T. Hubbard, Thomas C. Gent, Marieke MB Hoekstra, Yann Emmenegger, Valérie Mongrain, Hans‐Peter Landolt, Antoine Adamantidis, Paul Franken

The paper re-evaluates slow-wave dynamics as a proxy for NREM sleep homeostasis, finding distinct delta-wave types with different responses to sleep deprivation and recovery.

Nature Communications · Jun 19, 2020Peer-reviewedNeuroscience

Melanopsin-dependent direct photic effects are equal to clock-driven effects in shaping the nychthemeral sleep-wake cycle

Jeffrey T. Hubbard, Mio Kobayashi Frisk, Élisabeth Ruppert, Jessica W. Tsai, Fanny Fuchs, Ludivine Robin-Choteau, Jana Husse, Laurent Yves Calvel, Gregor Eichele C, Paul Franken, Patrice Bourgin

The paper shows that direct photic effects and circadian-driven effects equally shape the sleep-wake cycle in mice, with melanopsin mediating most direct light effects.

bioRxiv · Feb 21, 2020 · PreprintNeuroscience

Simple and complex interactions between sleep-wake driven and circadian processes shape daily genome regulatory dynamics in the mouse

Charlotte N. Hor, Jake Yeung, Maxime Jan, Yann Emmenegger, Jeffrey T. Hubbard, Ioannis Xénarios, Félix Naef, Paul Franken

This study examines how sleep deprivation affects gene expression and chromatin accessibility in mice, revealing long-term genomic regulatory changes.

Proceedings of the National Academy of Sciences · Nov 27, 2019Peer-reviewedGenomics

Cold Inducible RNA-binding protein (CIRBP) adjusts clock gene expression and REM sleep recovery after sleep deprivation

Marieke MB Hoekstra, Yann Emmenegger, Jeffrey T. Hubbard, Paul Franken

This study shows that CIRBP modulates clock gene expression and REM sleep recovery after sleep deprivation in mice.

eLife · Feb 5, 2019Peer-reviewedNeuroscience