Author

Jane C. Atkinson

Massachusetts Institute of Technology

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Systems Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Brittany A Lende-DorniD· 1 shared Kate E. GallowayiD· 1 shared Yunbeen BaeiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperSystems Biology

Brittany A Lende-DornORCID

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1 paper

Recent·Most cited

Chemogenetic tuning reveals optimal MAPK signaling for cell-fate programming

Brittany A Lende-Dorn, Jane C. Atkinson, Yunbeen Bae, Kate E. Galloway

This study shows that optimal MAPK signaling levels enhance direct conversion of fibroblasts to motor neurons, while excessive levels induce senescence and reduce conversion rates.

Cell Reports · Sep 1, 2025Peer-reviewedSystems Biology