Author

Yunbeen Bae

Massachusetts Institute of TechnologyORCID 0000-0002-6472-2550Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Synthetic Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Brittany A Lende-DorniD· 2 shared Kate E. GallowayiD· 2 shared Adam M. BeitziD· 1 shared Deon S. PloessliD· 1 shared Emma L. PetermaniD· 1 shared Jane C. Atkinson· 1 shared Kasey S. LoveiD· 1 shared Mary Elisabeth EhmanniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersSynthetic Biology

Brittany A Lende-DornORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Programmable promoter editing for precise control of transgene expression

Sneha R Kabaria, Yunbeen Bae, Mary Elisabeth Ehmann, Brittany A Lende-Dorn, Adam M. Beitz, Emma L. Peterman, Kasey S. Love, Deon S. Ploessl, Kate E. Galloway

DIAL is a framework for designing synthetic promoters that generate heritable, tunable gene expression setpoints across cell types.

Nature Biotechnology · Oct 13, 2025Peer-reviewedSynthetic Biology

Chemogenetic tuning reveals optimal MAPK signaling for cell-fate programming

Brittany A Lende-Dorn, Jane C. Atkinson, Yunbeen Bae, Kate E. Galloway

This study shows that optimal MAPK signaling levels enhance direct conversion of fibroblasts to motor neurons, while excessive levels induce senescence and reduce conversion rates.

Cell Reports · Sep 1, 2025Peer-reviewedSystems Biology