Base-edited CAR T Cells for combinational therapy against T cell malignancies
Christos Georgiadis, Jane Rasaiyaah, Soragia Athina Gkazi, Roland Preece, Annie Etuk, Abraham Christi, Waseem Qasim
This study develops base-edited CAR T cells to overcome fratricide by removing shared antigens, showing enhanced cytotoxicity against T cell malignancies.
Leukemia · May 25, 2021Peer-reviewedMolecular Biology