Author

Janet S. Wiegand

University of Florida

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Daohong ZhouiD· 1 shared Frederic J. KayeiD· 1 shared Guangrong ZhengiD· 1 shared Lin Sen CaoiD· 1 shared Maria Zajac‐KayeiD· 1 shared Peiyi ZhangiD· 1 shared Sajid Ullah KhaniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Daohong ZhouORCID

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1 paper

Recent·Most cited

Cancer BiologyCellsPeer-reviewedMar 17, 2024

PROTAC-mediated dual degradation of BCL-xL and BCL-2 is a highly effective therapeutic strategy in small-cell lung cancer

Sajid Ullah Khan, Lin Sen Cao, Janet S. Wiegand…·Daohong Zhou

This paper evaluates a dual BCL-xL/BCL-2 degrader, 753b, showing it effectively reduces tumor viability and growth in SCLC models while avoiding platelet toxicity seen with navitoclax.

43 citationstop 3%

mouseexperimental assay