The Ca2+-Sensitivity of Contraction is Increased in the Left Atrium and Left Ventricle of Patients with Ischemic Heart Failure
Gregory N. Milburn, Chloe I Roth, Jania Bell, Austin G. Wellette‐Hunsucker, Marziyeh Pakbaz, Alexandre Lewalle, Steven Niederer, Kenneth S. Campbell
This study examines changes in calcium sensitivity and contractile properties of left atrial and ventricular myocardium in ischemic heart failure, finding increased calcium sensitivity and altered kinetics in the left atrium.
bioRxiv · Jul 1, 2026 · PreprintPhysiology