BiochemistryEuropean Journal of Medicinal ChemistryPeer-reviewed
Synthesis and evaluation of chemical linchpins for highly selective CK2α targeting
Francesco A. Greco, Andreas Krämer, Laurenz Wahl…·Stefan Knapp
The paper designs and evaluates chemical linchpins targeting CK2α with a novel binding mode combining allosteric and ATP competitive elements, showing high selectivity and low micromolar activity.