A Proximity-Driven Functional Screening Platform for the Discovery of Noninhibitory USP7 Ligand Enabling Targeted Protein Stabilization
Kate E Young, Janitha Kumarathunga, Hiruni Kandambi, Vitoria Fernandes Ferro, Weijun Gui
This paper introduces a proximity-driven screening platform to identify noninhibitory DUB ligands, discovering a USP7 ligand that enables targeted protein stabilization.
bioRxiv · Sep 14, 2026 · PreprintBiochemistry