Enhanced RNA Formation Under Amine-Rich Local Atmospheres from 2',3'- Cyclic Nucleotides
Almuth Schmid, Aleš Kovářík, Jara Hintz, Sreekar Wunnava, Jan Palacký, Miroslav Krepl, Ondřej Šedo, Štěpán Havel, Katarzyna Anna Ślepokura, Jiřı́ Šponer, Peter Mojzeš, Christof Bernhard Mast, Zbyněk Zdráhal, Dieter Braun, Judit E. Šponer
This study shows that ammonium and alkylammonium counterions enhance RNA polymerization from 2,3-cyclic nucleotides under dry, geologically plausible conditions.
bioRxiv · Mar 25, 2026 · PreprintBiochemistry