Mechanism of ERK-mediated Rho Activation and Stress Fiber Assembly for Cell Migration
Akib M. Khan, Jakaria Shawon, Jared P. Bergman, Keith R. Carney, Michelle C. Mendoza
This study identifies the mechanism by which ERK activates Rho and stress fibers through inhibition of Ezrin via phosphorylation of LOK, facilitating cell migration.
bioRxiv · Nov 15, 2025 · PreprintCell Biology