Jason G. Kralj

Reversible decrease in swimming motility accompanies emergent β-lactam antibiotic resistance in Escherichia coli

This study shows that reduced swimming motility accompanies B-lactam antibiotic resistance in E. coli through efflux mechanisms, with motility recovery after antibiotic removal.

A mathematical framework to correct for compositionality in microbiome datasets

This paper introduces a mathematical framework using internal standards to correct compositional biases in microbiome datasets, improving accuracy and precision in taxa abundance measurements.

Analytical Assessment of Metagenomic Workflows for Pathogen Detection with NIST RM 8376 and Two Sample Matrices

The paper evaluates metagenomic workflows for pathogen detection using NIST RM 8376 in CSF and stool samples, finding workflow-dependent strain discrimination and sample-agnostic detection responses.

Considerations for performance metrics of metagenomic next generation sequencing analyses

The paper discusses considerations for performance metrics in metagenomic NGS analyses, emphasizing the need for taxon-specific evaluation and appropriate summary metrics.