Jennifer N. Dootz

Measurement Quality Metrics to Improve Absolute Microbial Cell Counting

This paper develops and demonstrates modified quality metrics for microbial cell counting methods to improve accuracy and comparability across different techniques.

A mathematical framework to correct for compositionality in microbiome datasets

This paper introduces a mathematical framework using internal standards to correct compositional biases in microbiome datasets, improving accuracy and precision in taxa abundance measurements.

Analytical Assessment of Metagenomic Workflows for Pathogen Detection with NIST RM 8376 and Two Sample Matrices

The paper evaluates metagenomic workflows for pathogen detection using NIST RM 8376 in CSF and stool samples, finding workflow-dependent strain discrimination and sample-agnostic detection responses.

Measuring Microbial Community-Wide Antibiotic Resistance Propagation via Natural Transformation in the Human Gut Microbiome

This study demonstrates that extracellular antibiotic resistance genes (eARGs) can be taken up and expressed by gut microbes, promoting antibiotic resistance propagation through natural transformation.