Iron and Heme Coordinate Erythropoiesis through HRI-Mediated Regulation of Protein Translation and Gene Expression
Shuping Zhang, Alejandra Macias-Garcia, Jacob C. Ulirsch, Jason Velazquez, Vincent L. Butty, Stuart S. Levine, Vijay G. Sankaran, Jane-Jane Chen
The paper investigates how iron, heme, and HRI regulate protein translation and gene expression in erythroblasts during iron deficiency, identifying novel pathways and regulators of erythropoiesis.
bioRxiv · Sep 4, 2018 · PreprintCell Biology