Heightened subcortical reactivity to uncertain-threat is associated with future internalizing symptoms, conditional on stress exposure
Shannon E. Grogans, Kathryn A. DeYoung, Juyoen Hur, Allegra S. Anderson, Samiha Islam, Hyung Cho Kim, Jazmine Wedlock, Logan E. Craig, Rachael M. Tillman, Sanjana Das, Manuel Kuhn, Christopher Conway, Andrew S. Fox, Jason F. Smith, Alexander J. Shackman
The paper identifies heightened subcortical reactivity to uncertain-threat as a predictor of future internalizing symptoms in individuals with low stress exposure.
bioRxiv · Jun 11, 2025 · PreprintNeuroscience