Manuel Kuhn

This study examines changes in anterior cingulate cortex connectivity in response to antidepressant treatment in MDD patients, finding distinct patterns associated with treatment response and remission.

This study shows that acute stress reorganizes neural coupling in rMDD patients during decision-making, predicting future depressive symptoms.

This study shows that recent adversity reduces autonomic threat-safety discrimination and predicts higher depression levels later, with distinct brain activation patterns linked to these effects.

The paper analyzes fMRI data to investigate the role of the extended amygdala in threat processing, finding no strict functional segregation between the central nucleus and bed nucleus of the stria terminalis.

The paper identifies heightened subcortical reactivity to uncertain-threat as a predictor of future internalizing symptoms in individuals with low stress exposure.

This study examines PNOC and OPRL1 expression in Alzheimer's disease, finding sex differences and associations with psychiatric symptoms and circadian disruption.

This paper demonstrates that certain and uncertain threat anticipation recruit a shared neural circuit with distinct activation dynamics in humans.

The paper investigates the neural basis of neuroticism/negative emotionality by showing its association with heightened BST activation during uncertain threat anticipation, not the amygdala.

The paper examines whether similar affective experiences produce comparable physiological responses, finding strong evidence for individual variability in physiological responses to affective stimuli.

This study examines reliability and response prediction in fear conditioning across time and phases, finding limited individual-level longitudinal reliability but some cross-phase predictability.

The paper links greater activation in a cingulo-opercular circuit during an anxiety-eliciting task with reduced daily stressor-related distress in individuals.

This study investigates the neural circuits involved in anticipating temporally uncertain and certain threat, revealing co-localized but functionally distinct brain regions associated with anxiety.

This study uses combined facial EMG-fMRI to show that the human startle reflex is modulated by valence-specific neural pathways involving the amygdala and brainstem.