Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10
Jeanne Corriveau, Pascale Monot, Chantal Delisle, Marie-Anne Goyette, Camille Gasse, Yassine El Bakkouri, T. Hoang, Jean‐François Côté, Jean‐Philippe Gratton
This study shows that inhibiting PAK2 in endothelial cells reduces tumor angiogenesis and enhances immune cell infiltration via CXCL10 secretion.
Cell Reports · Dec 30, 2025Peer-reviewedCancer Biology