Jean‐François Côté

This study shows that inhibiting PAK2 in endothelial cells reduces tumor angiogenesis and enhances immune cell infiltration via CXCL10 secretion.

This study shows Dock8 regulates mechanosensitive actin redistribution in immune cells, maintaining cohesion and protecting the nucleus during migration through confined environments.

The paper investigates how multiple FGFR1 mutations affect tumorigenic mechanisms in glioneuronal tumors by analyzing their interactomes and functional impacts.

The paper maps the interactome of ARF and ARL proteins using BioID, identifies new localizations, and reveals functional roles of ARL14 in activating PLD1 and cargo trafficking.

The paper identifies C1orf112 as a novel regulator of interstrand crosslinks that decreases FIGNL1-RAD51 interaction, impairing homology-directed repair.

The paper shows GFI1 recruits the NuRD complex to open chromatin regions in myeloid progenitors, influencing chromatin structure and gene regulation during neutrophil differentiation.

This study identifies POGZ as a regulator of HP1-dependent DNA repair, showing its role in homology-directed repair and its clinical relevance to White Sutton syndrome.