Multimodal gene and targeted drug therapy for chronic myelogenous leukemia: Computational target analysis and therapeutic validation
Margaret L. Lugin, Winnie Lei, Rebecca T. Lee, Jee Young Chung, Nicholas M. Katritsis, Woochang Hwang, Angela G. Fleischman, Namshik Han, Young Jik Kwon
This paper develops a multimodal therapy for CML combining computational target analysis with nanoparticle-based drug delivery and validates its efficacy in mouse models.
bioRxiv · May 26, 2025 · PreprintCancer Biology