Plagl1 is part of the mammalian retinal injury response and a critical regulator of Muller glial cell quiescence
Yacine Touahri, Luke Ajay David, Yaroslav Ilnytskyy, Edwin van Oosten, Joseph Hanna, Nobuhiko Tachibana, Lata Adnani, Jiayi Zhao, Mary Hoffman, Rajiv Dixit, Laurent Journot, Yves Sauvé, Igor Kovalchuk, Isabelle Aubert, Jeffrey Biernaskie, Carol Janine Schuurmans
The paper identifies Plagl1 as a regulator of Muller glial quiescence in the mammalian retina, showing its role in preventing reactive gliosis and neurogenesis after injury.
bioRxiv · Apr 12, 2021 · PreprintNeuroscience