Yacine Touahri

Etv5 is not required for Schwann cell development but is required to regulate the Schwann cell response to peripheral nerve injury

This study shows Etv5 is not needed for Schwann cell development but is essential for regulating their response to peripheral nerve injury.

NEUROG2 regulates a human-specific neurodevelopmental gene regulatory program

The paper identifies NEUROG2's role in regulating a human-specific gene regulatory program in neural progenitor cells through transcriptomic analysis of knock-in organoids.

Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling

The paper shows glycolytic flux promotes rod photoreceptor differentiation by regulating Wnt signaling in murine retinal progenitor cells.

Pten regulates endocytic trafficking of cell adhesion and signaling molecules to pattern the retina

This study shows Pten and Dscam regulate amacrine cell spacing through endocytic trafficking of cell adhesion and signaling molecules, with altered extracellular vesicles and Wnt signaling in Pten mutants.

Proneural genes define ground state rules to regulate neurogenic patterning and cortical folding

The paper shows Neurog2 and Ascl1 genes regulate cortical progenitor differentiation and folding through Notch signaling in lissencephalic brains.

Plagl1 is part of the mammalian retinal injury response and a critical regulator of Muller glial cell quiescence

The paper identifies Plagl1 as a regulator of Muller glial quiescence in the mammalian retina, showing its role in preventing reactive gliosis and neurogenesis after injury.