Carol Janine Schuurmans

This study shows that focused ultrasound-mediated BBB modulation increases oligodendrogenesis by stimulating OPC proliferation in the hippocampus and striatum.

This study uses HR-MAS NMR to analyze metabolism in human-derived cerebral organoids at different developmental stages, finding a metabolic profile similar to the human brain with some differences.

This study shows Etv5 is not needed for Schwann cell development but is essential for regulating their response to peripheral nerve injury.

The paper identifies NEUROG2's role in regulating a human-specific gene regulatory program in neural progenitor cells through transcriptomic analysis of knock-in organoids.

The paper shows glycolytic flux promotes rod photoreceptor differentiation by regulating Wnt signaling in murine retinal progenitor cells.

This study shows Pten and Dscam regulate amacrine cell spacing through endocytic trafficking of cell adhesion and signaling molecules, with altered extracellular vesicles and Wnt signaling in Pten mutants.

This study reprograms early cortical astroglia into neurons with parvalbumin-positive interneuron features using a modified Ascl1 protein.

The paper identifies a proneural gene combinatorial code that diversifies neocortical neural progenitor cells through gene regulatory networks and cell fate decisions.

This study shows that Ascl1 induces low-efficiency neuronal reprogramming of proliferative glia in vivo, unlike its efficient in vitro conversion.

The paper shows Neurog2 and Ascl1 genes regulate cortical progenitor differentiation and folding through Notch signaling in lissencephalic brains.

The paper identifies Plagl1 as a regulator of Muller glial quiescence in the mammalian retina, showing its role in preventing reactive gliosis and neurogenesis after injury.