Overexpression of a Gene That Modulates Cyclic-di-GMP Enhances Granulation in Mycobacterium smegmatis
Tiffany Lam, Samantha J. Belculfine, Kate N Gregory, Joseph Gitau Gikonyo, Jeffrey J. Kane, Chul Park, Yasu S. Morita
This study shows that overexpressing dcpA in Mycobacterium smegmatis enhances granulation and granule stability, suggesting c-di-GMP modulation plays a key role in microbial aggregation.
Biotechnology and Bioengineering · Aug 12, 2026Peer-reviewedBioengineering