Blood-based untargeted metabolomics in Relapsing-Remitting Multiple Sclerosis revealed the testable therapeutic target
Insha Zahoor, Hamid Suhail, Indrani Datta, Mohammad Ejaz Ahmed, Laila Poisson, Jeffrey Waters, Faraz Rashid, Bin Rui, Jaspreet Singh, Mirela Cerghet, Ashok Kumar, Md Nasrul Hoda, Ramandeep Rattan, Ashutosh Kumar Mangalam, Shailendra Giri
The paper identifies altered metabolic pathways in RRMS patients using metabolomics and shows that targeting glycolysis can reduce disease progression in a mouse model.
Proceedings of the National Academy of Sciences · Jun 14, 2022Peer-reviewedNeuroscience