Insha Zahoor

This study identifies Irg1 as a protective gene that negatively regulates pathogenic Th17 cells in CNS autoimmunity using knockout mice and single-cell RNA sequencing.

This study uses SIMOA to profile blood-based neural biomarkers and cytokines in EAE models, identifying NFL, GFAP, and IL-10 as potential predictors of disease activity.

This study uses untargeted metabolomics to identify altered serum metabolites distinguishing relapsing-remitting MS, progressive MS, and healthy subjects.

The paper identifies altered omega fatty acid-derived lipid mediators in RRMS patients using metabolipidomics, suggesting their potential as biomarkers for diagnosis and prognosis.

This study shows that MaR1 treatment reduces inflammation, protects neurons, and improves metabolism in a mouse model of multiple sclerosis.

This study shows that pyruvate dehydrogenase (Pdh) activity is critical for oligodendrocyte maturation and remyelination by regulating mitochondrial respiration and Olig1 acetylation.

The paper identifies altered metabolic pathways in RRMS patients using metabolomics and shows that targeting glycolysis can reduce disease progression in a mouse model.