Loss of AMPK potentiates inflammation by activating the inflammasome after traumatic brain injury in mice.
Mohammad Ejaz Ahmed, Hamid Suhail, Mohammad Nematullah, Md Nasrul Hoda, Shailendra Giri, Abdullah Shafique Ahmad
This study shows that loss of AMPK after traumatic brain injury in mice worsens inflammation and behavioral outcomes by increasing inflammasome activation and proinflammatory cytokines.
bioRxiv · Jun 25, 2024 · PreprintNeuroscience