Author

Jeffrey West

Primary ORCID profile (0000-0001-9579-4664 · 9 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Jeffrey WestiD9 papers · Moffitt Cancer Center

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Paul K. Newton· 2 shared Alexandra Ardaseva· 1 shared Cathal Harmon· 1 shared Davide Maestrini· 1 shared Derek Park· 1 shared Drew Williamson· 1 shared Hung Khong· 1 shared Kimberly Luddy· 1 shared

Activity by Year

2018-2018 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

Paul K. Newton

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3 papers

Recent·Most cited

Evolutionary exploitation of PD-L1 expression in hormone receptor positive breast cancer

Jeffrey West, Derek Park, Cathal Harmon, Drew Williamson, Peter Ashcroft, Davide Maestrini, Alexandra Ardaseva, Rafael Bravo, Prativa Sahoo, Hung Khong, Kimberly Luddy, Mark Robertson-Tessi

The paper models how timing of aromatase inhibitor and immune checkpoint inhibitor therapies affects tumor burden and metastatic potential in hormone receptor positive breast cancer.

bioRxiv · Oct 26, 2018 · PreprintCancer Biology

Cellular cooperation shapes tumor growth: a statistical mechanics mathematical model

Jeffrey West, Paul K. Newton

The paper develops a statistical mechanics model to link cellular cooperation and heterogeneity to macroscopic tumor growth laws, showing that cell-state correlations determine growth characteristics.

bioRxiv · Mar 8, 2018 · PreprintCancer Biology

Competitive release in tumors

Yongqian Ma, Jeffrey West, Paul K. Newton

The paper explores competitive release in tumors as a mechanism for chemotherapeutic resistance and proposes mathematical models to guide adaptive therapeutic strategies.

bioRxiv · Feb 10, 2018 · PreprintCancer Biology