Author

Mark Robertson-Tessi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Kimberly Luddy· 2 shared Alexander R. A. Anderson· 1 shared Alexander RA Anderson· 1 shared Alexandra Ardaseva· 1 shared Casey Adams· 1 shared Cathal Harmon· 1 shared Chandler D. Gatenbee· 1 shared Charlie Daneils· 1 shared

Activity by Year

2016-2018 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

Kimberly Luddy

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Evolutionary exploitation of PD-L1 expression in hormone receptor positive breast cancer

Jeffrey West, Derek Park, Cathal Harmon, Drew Williamson, Peter Ashcroft, Davide Maestrini, Alexandra Ardaseva, Rafael Bravo, Prativa Sahoo, Hung Khong, Kimberly Luddy, Mark Robertson-Tessi

The paper models how timing of aromatase inhibitor and immune checkpoint inhibitor therapies affects tumor burden and metastatic potential in hormone receptor positive breast cancer.

bioRxiv · Oct 26, 2018 · PreprintCancer Biology

Non-linear tumor-immune interactions arising from spatial metabolic heterogeneity

Mark Robertson-Tessi, Robert J. Gillies, Robert A. Gatenby, Alexander R. A. Anderson

This study uses a hybrid mathematical model to show that immune response to tumors depends on spatial metabolic heterogeneity and varies across tumor growth stages.

bioRxiv · May 4, 2016 · PreprintCancer Biology

Exploiting Homeostatic Repopulation to Increase DC Vaccine Efficacy in Multiple Myeloma

Chandler D. Gatenbee, Núria Folguera-Blasco, Charlie Daneils, Jill Gallaher, Russell C. Rockne, Casey Adams, Michael Nicholson, Eleni Maniati, John Kennedy, Kimberly Luddy, Frederick L. Locke, Mark Robertson-Tessi

This paper tests a dendritic cell vaccine in multiple myeloma patients before and after AHCT to improve outcomes and uses a model to guide future trials.

bioRxiv · Apr 22, 2016 · PreprintCancer Biology

Stochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-Hedging

Daniel Nichol, Mark Robertson-Tessi, Peter Jeavons, Alexander RA Anderson

This paper explores the genotype-phenotype map using molecular switches to show how robustness and persistence emerge, explaining bet-hedging strategies and their implications for treatment resistance.

bioRxiv · Mar 4, 2016Evolutionary Biology