Repurposing the yeast peroxisome to compartmentalize a toxic enzyme enables improved (S)-reticuline production
Parbir S. Grewal, Jennifer A. Samson, Jordan J. Baker, Brian Choi, John E. Dueber
This study repurposes the yeast peroxisome to compartmentalize a toxic enzyme, improving (S)-reticuline production by reducing NCS toxicity and increasing BIA titer.
bioRxiv · Mar 23, 2020 · PreprintSynthetic Biology