John E. Dueber

This paper describes an engineered E. coli strain that produces long single-stranded DNA efficiently, validated for use in genome editing and DNA origami.

This paper improves the microbial synthesis of benzylisoquinoline alkaloids in yeast by using human monoamine oxidase A to increase selectivity and yield of (S)-reticuline and its derivatives.

This study repurposes the yeast peroxisome to compartmentalize a toxic enzyme, improving (S)-reticuline production by reducing NCS toxicity and increasing BIA titer.

This study identifies an efficient pathway for D-galacturonic acid metabolism in Rhodosporidium toruloides, demonstrating its potential for pectin-rich waste conversion.

This paper describes a yeast platform that significantly increases the production of tetrahydroisoquinoline alkaloids, enabling the synthesis of natural and unnatural derivatives.