Analysis of gliomas DNA methylation: Assessment of pre-analytical variables.
Karol Bomsztyk, Daniel Mar, Oleg N. Denisenko, Suzanne Zein-Eldin Powell, Monika Vishnoi, Zheng Qin Yin, Jennifer Delegard, Caroline C. Hadley, Nitin Tandon, Akash J. Patel, Anoop P. Patel, Richard G. Ellenbogen, Rohan R. Ramakrishna, Robert Rostomily
This study assesses how pre-analytical variables affect DNA methylation analysis of the MGMT promoter in gliomas, finding that most variations do not significantly impact results but intratumor heterogeneity is prevalent.
Laboratory Investigation · Oct 18, 2024Peer-reviewedMolecular Biology