Oleg N. Denisenko

This study assesses how pre-analytical variables affect DNA methylation analysis of the MGMT promoter in gliomas, finding that most variations do not significantly impact results but intratumor heterogeneity is prevalent.

The paper introduces a low-cost system for high-throughput RNA isolation from tissues, combining CryoGrid for storage/sampling with PIXUL-based methods using a PK buffer to enable efficient transcript analysis.

The paper introduces MultiomicsTracks96, a high-throughput multi-omics workflow for analyzing frozen and FFPE tissues, showing high correlation between data types and improved protein prediction using multi-omics data.