Tyrosine kinase inhibitors affect sweet taste and dysregulate fate selection of specific taste cell subtypes via KIT inhibition.
Christina M. Piarowski, Jennifer K. Scott, Courtney Wilson, Heber I. Lara, Ernesto E. Salcedo, Andrew S. Han, Elaine T. Lam, Peter J. Dempsey, Jakob von Moltke, Linda A. Barlow
This study shows that tyrosine kinase inhibitors cause taste dysfunction by altering the fate of taste cell subtypes through KIT inhibition.
Development · Apr 15, 2026Peer-reviewedNeuroscience