Microglia respond to elevated intraocular pressure and synapse loss in the visual thalamus in a mouse model of glaucoma.
Jennifer L. Thompson, Shaylah McCool, JENNIE SMITH, Victoria L. Schaal, Gurudutt Pendyala, Sowmya V. Yelamanchili, Matthew J. Van Hook
This study examines microglia morphology and gene expression in the visual thalamus of glaucoma mice, finding morphological changes and immune gene upregulation linked to intraocular pressure and synapse loss.
bioRxiv · Oct 25, 2024 · PreprintNeuroscience