Shaylah McCool

Plaque-associated Microglial Polarization in Visual Brain Regions of the 5xFAD Mouse Model

The paper examines Aβ pathology and microglial responses in visual brain regions of 5xFAD mice, finding significant Aβ accumulation and microglial polarization in image-forming regions but not in non-image-forming regions.

Compensatory responses to glaucoma pathology in the dorsolateral geniculate nucleus

This study investigates compensatory plasticity in the dorsolateral geniculate nucleus of glaucomatous mice, finding increased intrinsic excitability and reduced inhibition in relay neurons despite diminished retinal input.

Microglia respond to elevated intraocular pressure and synapse loss in the visual thalamus in a mouse model of glaucoma.

This study examines microglia morphology and gene expression in the visual thalamus of glaucoma mice, finding morphological changes and immune gene upregulation linked to intraocular pressure and synapse loss.

Amyloid Beta Pathology Accelerates Alterations in the Visual Pathway of the 5xFAD Mouse

This study examines the impact of amyloid beta pathology on the visual pathway in 5xFAD mice, finding modest dysfunction and potential compensatory mechanisms.

Nonuniform scaling of synaptic inhibition in the dorsolateral geniculate nucleus in a mouse model of glaucoma.

The paper investigates inhibitory synaptic changes in the dLGN of glaucomatous mice and finds non-uniform upregulation of GABA receptors at inhibitory synapses.