Single-Nucleus Transcriptomics Reveals Cell Type-Specific Remodeling and Epilepsy-Associated Microglia
Victoria M. Ho, Ruth Tjondropurnomo, Jennifer Nguyen, Eszter Balko, Samantha Depew, Xing Chen, Radhika Singh, J. Edward van Veen, Bence Rácz, Peyman Golshani
The paper uses single-nucleus RNA sequencing to identify cell type-specific changes in a mouse model of mesial temporal lobe epilepsy, highlighting an epilepsy-associated microglia population with unique transcriptomic features.
iScience · Aug 19, 2026Peer-reviewedNeuroscience