Bence Rácz

Single-Nucleus Transcriptomics Reveals Cell Type-Specific Remodeling and Epilepsy-Associated Microglia

The paper uses single-nucleus RNA sequencing to identify cell type-specific changes in a mouse model of mesial temporal lobe epilepsy, highlighting an epilepsy-associated microglia population with unique transcriptomic features.

Preserved functions with profound morphological reorganization in human organotypic cultures

This study tracks functional and structural changes in human cortical slice cultures over weeks, finding stable functional states despite structural degradation.

Presynaptic Rac1 in the hippocampus selectively regulates working memory

This study shows that presynaptic Rac1 signaling selectively regulates spatial working memory, with distinct effects on synaptic vesicles and morphology compared to postsynaptic Rac1 inhibition.

Action potential-coupled Rho GTPase signaling drives presynaptic plasticity

This study identifies Rac1 and Arp2/3 as key regulators of presynaptic plasticity through proteomic analysis and shows their coupling to action potentials via calcium influx.

Reduced prefrontal synaptic connectivity and disturbed oscillatory population dynamics in the CNTNAP2 model of autism

This study investigates the effects of CNTNAP2 loss-of-function mutations in mice, finding reduced synaptic connectivity and altered oscillatory dynamics in the prefrontal cortex associated with autism-like behaviors.