J. Edward van Veen

The paper identifies pituitary macrophages as hormone-producing immune cells that regulate gonadotropin secretion through CXCL5-CXCR2-MAPK signaling in female mice.

The paper uses single-nucleus RNA sequencing to identify cell type-specific changes in a mouse model of mesial temporal lobe epilepsy, highlighting an epilepsy-associated microglia population with unique transcriptomic features.

This paper introduces a bifunctional optical reporter, neuro-seeER, to track estrogen response dynamics in neurons in vivo and demonstrates its utility in capturing both exogenous and endogenous estrogen responses.

This study shows estrogen signaling in Reprimo lineage cells affects thermoregulation in female mice by altering brown adipose tissue thermogenesis, but not in males.

The paper establishes a database of lung cancer mouse models to improve data comparison and translational relevance by aligning mouse mutations with human lung cancer mutations.

This study identifies TNSST neurons in mice that modulate feeding behavior based on metabolic and reproductive states, with effects dependent on body mass and estrogen levels.

This study identifies hypothalamic estrogen receptor alpha as a mediator of tamoxifen-induced side effects in mice through single-cell RNA sequencing and genetic knockout experiments.

The paper identifies six distinct neuron clusters in the VMH using single-cell RNA sequencing and shows sex-specific differences in gene expression and function related to energy expenditure.