Genes involved in protein folding and chromatin organization buffer genetic variation
Jens Frickel, Mohammed Talib Tawfeeq, Emily Baker, Sara Baco, Jonas Rombout, Karin Voordeckers, Daniel F. Jarosz, Sibylle Chantal Vonesch, Kevin J. Verstrepen
The paper identifies buffer genes in yeast that influence the phenotypic effects of mutations by modulating genetic variation's impact on fitness.
bioRxiv · Sep 24, 2024 · PreprintEvolutionary Biology