Kevin J. Verstrepen

The paper analyzes 178 genomes of Kluyveromyces marxianus to show two distinct evolutionary trajectories within the species, one linked to domestication and the other to deep lineage divergence.

The paper identifies buffer genes in yeast that influence the phenotypic effects of mutations by modulating genetic variation's impact on fitness.

The paper identifies Fpt1 as a chromatin-associated regulator that promotes RNA Polymerase III eviction from tRNA genes in response to nutrient changes in yeast.

The paper benchmarks long-read assembly pipelines using 116 yeast datasets, finding that combining pre-assembly short-read error correction with post-assembly polishing yields the best results.