ImmunologyCell Host & MicrobePeer-reviewed
A TRADE-OFF BETWEEN RESISTANCE TO INFECTION AND REPRODUCTION IN PRIMATE EVOLUTION
Sumnima Singh, Jessica A. Thompson, Sebastian Weis…·Miguel P. Soares
The paper shows that loss of GGTA1 function in mice increases resistance to sepsis via enhanced IgG-Fc gamma receptor binding but causes earlier reproductive senescence, suggesting a trade-off that may explain primate evolution.
DOI 10.1016/j.chom.2020.12.017