Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9
Joshua D Eaton, Jessica Board, Lee Davidson, Chris Estell, Steven West
The paper shows that sense transcription is more efficient than antisense initiation and that CDK9 and INTS11 opposingly maintain directionality in mammalian promoters.
eLife · Feb 12, 2024Peer-reviewedMolecular Biology