Structure and mechanism of human sphingosine-1-phosphate transporter MFSD2B
Shahbaz Ahmed, Min Huang, Yaxin Dai, Xuebo Yang, Jiajun Dong, Xiang Yu, Chia‐Hsueh Lee, Long Nam Nguyen
This study determines the cryo-EM structure of MFSD2B bound to S1P and identifies its transport mechanism through mutagenesis and simulations.
Nature Communications · Aug 12, 2026Peer-reviewedBiochemistry