Author
St. Jude Children's Research HospitalORCID 0000-0003-0819-6477Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Shahbaz Ahmed, Min Huang, Yaxin Dai…·Long Nam Nguyen
This study determines the cryo-EM structure of MFSD2B bound to S1P and identifies its transport mechanism through mutagenesis and simulations.
Jianxiang Zhang, Chao Yang, Yu Zhang…·Jiankun Lyu
The paper introduces CombiDOCK and MINT-Dock to efficiently screen large molecule libraries for ligand discovery, achieving high hit rates and computational efficiency.
Fangfang Lu, Hongtu Zhao, Yaxin Dai…·Matthew Freeman
This study identifies a sterol-binding pocket in iRhom1 that regulates ADAM17 stability and shedding activity, distinct from the paralog iRhom2.